CONSULTATIONS FOR REJURAN & POLYNUCLEOTIDES
Rejuran® is the brand name of a class of injectable treatments known as 'polynucleotides'. Rejuran is currently the only TGA-approved polynucleotide product available in Australia. Rejuran is not classified as a prescription medicine (an S4 drug) and therefore it can be mentioned by name unlike most other products used in aesthetics in Australia.
Rejuran is very different to other products such as facial volumisers, bio-hydrators, bio-remodellers or bio-stimulators. It is sometimes classified as a 'bio-regenerator' because it sits in a different category when compared to any other product.
Rejuran contains marine-derived (wild salmon) DNA fragments - the so called 'polynucleotides'. Despite what you might have read online, the DNA isn't sourced from salmon sperm. Instead it is sourced from the gonad tissue and this is of course then undergoes several manufacturing steps to purify and extract the DNA.
Rejuran is a clear, colourless and odourless solution which contains polynucleotides. The wild salmon used in Rejuran are under the strict authority of the Korean Fisheries Department. This means that their stocks are maintained, preserved and protected. They are not farmed, bred and no hormones or other additives are ever fed to the salmon, leading to the purest polynucleotide source in the world.
WHAT ARE POLYNUCLEOTIDES?
Polynucleotides are purified, bio-active DNA fragments. You can think of polynucleotides as 'building blocks' - when these added together in nature they build strands of DNA. Injectable polynucleotides are runny liquids in appearance and feel like a watery-serum to touch.
Rejuran is injected as multiple tiny dots just under the surface of the skin. Immediately after a treatment you will see some prominent and multiple raised dots all over the area of concern. This 'bumpy' look to the skin is very noticeable but only lasts for approximately 24-48 hours.
When injected, polynucleotides help stimulate your body's own regenerative and repair mechanisms. Rejuran has been used in Asia since 2014 and over 10 million syringes have been used to date.
HOW DO POLYNUCLEOTIDES WORK?
When injected, polynucleotides signal to the dermis layer of your skin via a number of different cellular pathways. In simple terms, polynucleotides help support your skin's own regenerative capabilities by:
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Stimulating the fibroblast cells to produce more collagen and hyaluronic acid
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Promoting and accelerating skin healing and repair by up-regulating angiogenesis (the formation of new blood vessels) and by down-regulating inflammation (reducing swelling and redness). Clinical studies based on smaller fragments (called polydeoxyribonucleotides or PRDN) have demonstrated impressive results for wound repair, scar remodelling, trauma injuries, burns and diabetic ulcers.
When injected, polynucleotides therefore help to turn on your body's own regenerative and repair mechanisms.
A huge advantage of polynucleotides is that they have never caused a vascular occlusion nor any other significant complications. This means the risk of blindness or stroke (that is associated with fillers) is essentially zero.
Korean doctors with nearly a decade of experience using Rejuran have also noticed how polynucleotides seems help improve issues like sensitive skin and redness. It's therefore also a very useful product when used in combination with laser treatments to improve healing and downtime from these treatments, but also to optimise the overall results. Those who suffer with rosacea or melasma might consider adding Rejuran into their overall skin treatment plan as it may help improve the health of the skin barrier in combination with other treatments.
KEY FEATURES OF REJURAN CONSULTATIONS
Consultations
New patient consultation + Rejuran treatments = 45 mins.
Existing patient consultations + treatments = 30 mins.
Skin quality improvement
Common areas to use Rejuran include the skin around the eyes, the rest of the face and neck. This can improve texture, firmness, crepiness as well as calming inflammation or redness.
How many treatments?
Initially 3 treatments are recommended, 2-4 weeks apart. This is followed by once every 3-6 months for maintenance.
Safety
Rejuran treatments will be visible for approximately 48 hours. Serious complications like vascular occlusions and blindness are not associated with polynucleotides.
